OC (BA/BSC 6th)

UNIT-I (8 Hrs.)

Amino Acids, Peptides, Proteins and Nucleic Acids:

Classification, structure and stereochemistry of amino acids. Acid- base behavior, isoelectric point and

electrophoresis. Preparation and reactions of α - amino acids.

Structure and nomenclature of peptides and proteins. Classification of proteins. Peptide structure

determination, end group analysis, selective hydrolysis of peptides. Classical peptide synthesis, solid – phase

peptide synthesis. Structures of peptides and proteins. Levels of protein structure. Protein

denaturation/renaturation.

Nucleic Acids : Introduction. Constituents of nucleic acids. Ribonucleosides and ribonucleotides. The double

helical Structure of DNA.

UNIT-II (7 Hrs.)

Synthetic Polymers:

Addition or chain-growth polymerization. Free radical vinyl polymerization, ionic vinyl polymerization, Ziegler – Natta polymerization and vinyl polymers.

Condensation or step growth polymerization. Polyesters, polyamides, phenol formaldehyde resins, urea formaldehyde resins, epoxy resins and polyurethanes.

Natural and synthetic rubbers.

UNIT-III (7 Hrs.)

Organic Synthesis via Enolates:

Acidity of ά-hydrogens, alkylation of diethyl malonate and ethyl acetoacetate. Synthesis of ethyl acetoacetate:

the Claisen condensation. Keto-enol tautomerism of ethyl acetoacetate. Alkylation and acylation of enamines.

UNIT-IV (8 Hrs.)

Organometallic Compounds:

Organomagnesium Compounds: The Grignard reagents – Formation, structure and chemical reactions.

Organozinc Compounds: Formation and Chemical reactions.

Organolithium Compounds: Formation and Chemical reactions.