OC (BA/BSC 4th)

Unit-I

Organic Chemistry of Life I: (05 Lectures)

Nucleic Acids : Nucleosides; Pentoses, heterocyclic bases, nucleotide; Purines and phosphate, DNA and RNA Hydrogen bonding and DNA replication (heredity).

Unit-II

Organic Chemistry of Life I: (05 Lectures)

Enzymes, nomenclature of enzymes, characteristics of enzymes, coenzyme A and prosthetic group. Coenzyme derived from niacin and examples of redox reaction with it.

Unit-III

Pericyclic Reactions I : (05 Lectures)

Electrocyclic Reactions: Woodward and Hoffmann rules, correlation diagram for cyclobutene = butadiene interconversion, Frontier orbital theory. Examples of 4, 6 and 8 electron systems, stereochemical modes.

Cycloaddition Reactions : Woodward and Hoffmann rules, Frontier Molecular orbital theory for Dieis-Alder reaction. 

Unit-IV

Pericyclic Reactions II: (05 Lectures)

(4+2) and (2+2) cycloadditions, exo and endo isomers, Examples Bicyclo (2, 2, 1) heptane and Bicyclo (2, 2, 2,) octane systems. Intramolecular Diels Alder reaction.

Sigmatropic Rearrangements: Woodward and Hoffmann rules, Frontier Molecular orbital for 1, 3; 1, 5 and 1, 7 shifts. Examples including vitamin D2 formation from 7-dehydro cholesterol (Provitamin D3).